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Collagen is used in bone grafting as it has a triple helical structure, making it a very strong molecule. Bone grafts Īs the skeleton forms the structure of the body, it is vital that it maintains its strength, even after breaks and injuries. Pathology of the collagen underpinning of the heart is understood within the category of connective tissue disease. Calcified points within collagen matrices show contrast in a moving display of blood and muscle, enabling methods of cardiac imaging technology to arrive at ratios essentially stating blood in ( cardiac input) and blood out ( cardiac output). Gradual calcium deposition within collagen occurs as a natural function of aging. Individual cardiac valvular leaflets are folded into shape by specialized collagen under variable pressure. The mass, distribution, age and density of collagen all contribute to the compliance required to move blood back and forth. Collagen is layered in variable densities with smooth muscle mass. With support from collagen, atrial fibrillation never deteriorates to ventricular fibrillation.
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The collagenous structure that divides the upper chambers of the heart from the lower chambers is an impermeable membrane that excludes both blood and electrical impulses through typical physiological means. Collagen contribution to the measure of cardiac performance summarily represents a continuous torsional force opposed to the fluid mechanics of blood pressure emitted from the heart. The cardiac skeleton also includes the separating septa of the heart chambers – the interventricular septum and the atrioventricular septum. The collagenous cardiac skeleton which includes the four heart valve rings, is histologically, elastically and uniquely bound to cardiac muscle. Type V: cell surfaces, hair, and placenta.Type IV: forms basal lamina, the epithelium-secreted layer of the basement membrane.Type III: reticulate (main component of reticular fibers), commonly found alongside type I.Type II: cartilage (main collagenous component of cartilage).Type I: skin, tendon, vasculature, organs, bone (main component of the organic part of bone).
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